The report is comprised of State profiles and findings that explain expenditure distributions for substance abuse prevention and treatment activities funded by the Substance Abuse Prevention and Treatment (SAPT) Block Grant and other funding sources for the 50 States and the District of Columbia. Other data contained in the report include State delivery systems for substance abuse prevention and treatment programming, information on treatment clients, treatment gap information, and resource development activities for the time period under examination. Narrative information is offered about the Single State Agency (SSA) structure, services, and activities. Nationally, State expenditures from the Block Grant and from State funds were roughly equal, with the Block Grant contributing approximately 42 percent of total State expenditures. States varied widely in the proportion of expenditures by funding source. In FY 2003, 19 States reported that most of their total expenditures were from the SAPT Block Grant, including Wisconsin, Alabama, and Texas. Another 13 States reported that most of their expenditures came from State funds, including New York, the District of Columbia, and Alaska. The majority of SSA expenditures were for treatment and rehabilitation services, which accounted for approximately 80 percent of total State expenditures between FY’s 2000 and 2003. Nationally, States spent more State funds on treatment services than Block Grant funds. Conversely, States spent more Block Grant funds on prevention services than State funds. Reports from 48 States indicated that treatment admissions totaled over 2 million in 2002. Most treatment admissions (66 percent) were for outpatient services. SSA expenditures on resource development activities from the Block Grant increased from 64 million in FY 2000 to 74 million in FY 2003. Resource development activities focused on planning, training, information technology, and quality assurance. Tables, figures, appendixes