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NCJ Number: NCJ 184373     Find in a Library
Title: Automated DNA Typing: Method of the Future?
Series: NIJ Research Preview
Author(s): Holly A. Hammond ; C. Thomas Caskey
Date Published: 02/1997
Page Count: 2
Sponsoring Agency: National Institute of Justice
US Department of Justice
Office of Justice Programs
United States of America
Grant Number: 90-IJ-CX-0037;92-IJ-CX-K042
Sale Source: US Dept of Justice NIJ Pub
810 Seventh Street, NW
Washington, DC 20531
United States of America
Document: Text PDF 
Type: Report (Technical)
Language: English
Country: United States of America
Annotation: This project sought a DNA typing system that overcomes the limitations of samples found at crime scenes.
Abstract: The project replicated the DNA sample, i.e., synthesized new DNA from existing DNA to obtain sufficient quantities for analysis and then identified genetic markers for DNA typing. This procedure, known as PCR-STR, can produce reliable results with degraded specimens, is quick, and can be automated to permit the creation of a vastly improved database of DNA profiles of convicted offenders. STR analysis was initially developed as a manual process, but automated methods are becoming available. The key to this technology is the use of fluorescent chemicals during the PCR process. A laser-generated fluorescent signal from the STR alleles passes information to a computer, where the collected data are analyzed to produce DNA profile information. In addition, robotic workstations are available to process DNA samples and assist with other procedures. With automation, the entire process, from DNA extraction to data interpretation, could be accomplished with little human involvement or manipulation, thereby reducing the possibility of error. PCR-STR promises to extend the application of DNA typing as a powerful criminal justice tool that helps to establish, with a high degree of certitude, the guilt or innocence of suspects. 3 notes
Main Term(s): Criminology
Index Term(s): Computer aided operations ; Science and Technology ; Forensics/Forensic Sciences ; Investigative techniques ; DNA fingerprinting
   
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https://www.ncjrs.gov/App/Publications/abstract.aspx?ID=184373

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