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NCJ Number: NCJ 239211     Find in a Library
Title: QuantAssure Cassette Development Research
  Document URL: PDF 
Author(s): Christian Carson ; Peter Sutovsky ; Glen Ford ; Dale Dembrow ; Joseph Gorman
Date Published: 2012
Page Count: 43
  Annotation: This research examines the development of a lateral flow cassette to identify the presence of sperm and semen in evidence samples.
Abstract: Results conclude that the effort to develop a polyclonal antibody by immunizing rabbits with the SPTRX3 exon5 peptide failed. The inability to develop SPTRX3 antibodies during the course of this project has prevented the intended effect of making the processing of rape kits in the forensic laboratory faster and more effective. BluePoint Bioscience immunized mice with the SPTRX3 exon1 peptide in order to develop a monoclonal antibody. This effort at SPTRX3 antibody development also failed. A second round of mouse immunizations met with the same fate. The inability to develop SPTRX3 antibodies brought the research project to a close. However, it is believed that the concept of developing a lateral flow cassette to determine the presence of spermatozoa and semen in evidence samples remains viable. Tables, figures, and references
Main Term(s): Forensics/Forensic Sciences
Index Term(s): Research and development ; Forensic pathology ; Rape research ; Rape evidence kits
Sponsoring Agency: National Institute of Justice (NIJ)
US Department of Justice
Office of Justice Programs
United States of America
Grant Number: 2008-IJ-CX-K007
Sale Source: NCJRS Photocopy Services
Box 6000
Rockville, MD 20849-6000
United States of America
Type: Report (Technical)
Country: United States of America
Language: English
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