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NCJRS Abstract

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NCJ Number: 250547 Find in a Library
Title: A Systematic Evaluation of the Analysis of Drug Microcrystals Using Infrared Microspectroscopy
Author(s): Monica Joshi
Corporate Author: University of Pennsylvania
United States of America
Date Published: August 2017
Page Count: 18
Sponsoring Agency: National Institute of Justice (NIJ)
Washington, DC 20531
University of Pennsylvania
Philadelphia, PA 19104
US Dept of Justice NIJ Pub
Washington, DC 20531
Grant Number: 2014-R2-CX-K008
Sale Source: US Dept of Justice NIJ Pub
810 Seventh Street, NW
Washington, DC 20531
United States of America
Document: PDF
Type: Program/Project Description; Report (Grant Sponsored); Report (Study/Research); Research (Applied/Empirical)
Format: Document; Document (Online)
Language: English
Country: United States of America
Annotation: This project’s purpose was to develop an infrared microspectroscopy method for drug micro crystals, with a focus on emerging novel psychoactive substances.
Abstract: It was anticipated that the combination of two uncorrelated techniques, microcrystalline tests and infrared microspectroscopy, would yield a rapid, cost-effective, and sensitive analytical scheme in which each of the techniques is strengthened by the other. The project succeeded in developing previously unreported microcrystalline tests for several novel psychoactive substances. The combination method was applied against six street psychoactive drug samples, successfully identifying the primary psychoactive substance in each of the samples. The benefits of this analytical scheme are that it is easy to perform, requires microgram quantities of samples, is cost-effective, and is effective as a screening technique for unknown drug samples. For forensic laboratories using the microcrystalline tests for routine identification of traditional drugs such as cocaine and heroin, having a reference library of photomicrographs of other drugs is a useful tool when faced with mixtures. During the 2-year period of the project, it performed a systematic study of microcrystalline tests for synthetic drugs; applied infrared microspectroscopy to the microcrystals and obtained molecular spectra of the crystals; developed a reference library of microcrystal photomicrographs and infrared spectra; and performed infrared microspectroscopy analysis of typical forensic drug samples. Details are provided on the microcrystalline tests and infrared micro spectroscopy. 5 references, listings of scholarly products and planned publications, and appended molecular structure of each of the psychoactive substances studied in the project
Main Term(s): Drug analysis
Index Term(s): Designer drugs; Forensic sciences; Infrared techniques; National Institute of Justice (NIJ); NIJ final report; Spectroscopy
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