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NCJ Number: 251376 Find in a Library
Title: Biometrics From the Isotopic Analysis of Amino Acids in Human Hair
Author(s): Glen P. Jackson
Corporate Author: West Virginia University
United States of America
Date Published: November 2017
Page Count: 46
Sponsoring Agency: National Institute of Justice (NIJ)
Washington, DC 20531
US Dept of Justice NIJ Pub
Washington, DC 20531
West Virginia University
Morgantown, WV 26506
Grant Number: 2013-DN-BX-K007
Sale Source: US Dept of Justice NIJ Pub
810 Seventh Street, NW
Washington, DC 20531
United States of America
Document: PDF
Type: Program/Project Description; Report (Grant Sponsored); Report (Study/Research); Research (Applied/Empirical)
Format: Document; Document (Online)
Language: English
Country: United States of America
Annotation: This project used isotope ratio mass spectrometry (TRMS) to analyze hair samples from a cohort of just over 200 subjects across the United States and Jordan.
Abstract: Project results provide evidence that compound-specific isotope ratio analysis of hair has the potential to go beyond information on region-of-origin or geospatial movements of individuals to include the identification of physical and characteristic traits of individuals, such as age and body mass index. By quantifying the amount of amino acids in human hair, researchers were able to perform statistical comparisons between donors with different characteristic traits, including sex, age, and region of origin. Using “leave-one-individual-out cross-validation” on more than 80 hair donors, the fuzzy rule-building expert system (FuRES) classification rate was 94 percent for sex, 83 percent for age group, and 61 percent for the region of origin. In addition, researchers used the amino acid profiles of scalp hair of 27 Jordanian subjects to predict diabetes from hair analysis. With FuRES, they were able to classify the amino acid profiles into diabetic and control groups with 100 percent sensitivity and specificity, using leave-one-individual-out cross-validation. The project contributed 100 data points to the publication of a new global database of bulk carbon and nitrogen isotope ratios in human hair containing more than 3,500 analysis results. This can be used by future investigators to provide statistical basis for inclusion or exclusion of evidence. In separate work, researchers used LC-TRMS to measure the isotope ratios of 14 amino acids in hair proteins independently, and leucine/isoleucine as a co-eluting pair to provide 15 variables for classification. Multivariate analysis confirmed that the essential amino acids and non-essential amino acids were mostly independent variables in the classification rules. 15 tables, 15 figures, 75 references, and a listing of sources for dissemination of research findings
Main Term(s): Forensic sciences
Index Term(s): Hair and fiber analysis; Investigative techniques; National Institute of Justice (NIJ); NIJ final report; Offender physical characteristics; Suspect identification
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