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NCJRS Celebrates National Library Week April 12-18

National Library Week

Started in 1958, National Library Week is a nationwide observance celebrated by all types of libraries - including the NCJRS Virtual Library. NCJRS invites you to explore the breadth and scope of the NCJRS Virtual Library collection and services. With more than 220,000 collection documents and 60,000 online resources, including all known Office of Justice Programs works, it is one of the world’s largest criminal justice special collections.

We encourage your Feedback. Tell us how you use the NCJRS Virtual Library and Abstracts Database, how you access the collection, and any ways we can improve our services.

NCJRS Abstract

The document referenced below is part of the NCJRS Library collection.
To conduct further searches of the collection, visit the NCJRS Abstracts Database.

How to Obtain Documents
 
NCJ Number: NCJ 241064     Find in a Library
Title: Cellular Immobilization within Microfluidic Microenvironments: Dielectophoresis with Polyelectrolyte Multilayers
Author(s): Samuel P. Forry ; Darwin R. Reyes ; Michael Gaitan ; Laurie E. Locascio
  Journal: Journal of the American Chemical Society  Volume:128  Issue:42  Dated:2006  Pages:13678 to 13679
Date Published: 2006
Page Count: 2
  Annotation: This article reports on the rapid, controllable immobilization of suspended mammalian cells within microfabricated environments, using a combination of electronic (dielectrophoresis, [DEP]) and chemical (polyelectrolyte multilayers, [PEMS]) forces.
Abstract: DEP trapping combined with PEMS surface modification provides a useful and reliable strategy for manipulating cellular position and adhesion. When combined with PEMS surface treatment, cell immobilization initiated by DEP is retained through substrate interactions, enabling removal of DEP forces and changes to solution composition without dislodging immobilized cells. Microfluidic delivery of chemicals to the trapping region facilitates nutrient delivery or cell monitoring and characterization, continuously or after delivery of soluble stimuli. Since dielectrophoresis can discriminate between cell types, it may be possible to systematically pattern discrete cell populations to create intricate co-cultures. In demonstrating for mammalian neural cells and pluripotent cells able to differentiate along, among others, neuronal pathways, this approach can be applied to assays within microenvironments for a variety of cell types. 1 figure and 30 references
Main Term(s): Forensics/Forensic Sciences
Index Term(s): Evidence collection ; Evidence identification and analysis ; Biological influences ; Investigative techniques ; NIJ grant-related documents
Sponsoring Agency: National Institute of Justice (NIJ)
US Department of Justice
Office of Justice Programs
United States of America
Grant Number: 2003-IJ-R-029
Type: Research (Applied/Empirical)
Country: United States of America
Language: English
   
  To cite this abstract, use the following link:
https://www.ncjrs.gov/App/Publications/abstract.aspx?ID=263152

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