skip navigation

CrimeSolutions.gov

Add your conference to our Justice Events calendar

PUBLICATIONS

NCJRS Abstract

The document referenced below is part of the NCJRS Library collection.
To conduct further searches of the collection, visit the NCJRS Abstracts Database.

How to Obtain Documents
 
NCJ Number: NCJ 241142     Find in a Library
Title: Allele Frequencies of Six MiniSTR Loci of Three Ethnic Populations in Singapore
Journal: Forensic Science International  Volume:166  Issue:2/3  Dated:2007  Pages:240 to 243
Author(s): R.Y.Y. Yong ; L.S.H. Gan ; M.D. Coble ; E.P.H. Yap
Date Published: 2007
Page Count: 4
Sponsoring Agency: National Institute of Justice
US Department of Justice
Office of Justice Programs
United States of America
Grant Number: 2003-IJ-R-029;D20030317
Type: Report (Study/Research)
Language: English
Country: United States of America
Annotation: This study examined the allele frequency of six miniSTR loci - D1S1677, D2S441, D4S2364, D10S1248, D14S1434, and D22S1045 - in three Singapore populations (Chinese, Malay, and Indian).
Abstract: MiniSTR loci have proven to be effective in recovering genetic information from degraded samples due to the improved PCR efficiency of their reduced PCR product sizes. The allele distribution of all six miniSTR loci proved that they are equally polymorphic in all three Singapore populations. In addition, their heterozygosity values are comparable to other world populations. The observed heterozygosity ranges from 0.600 to 0.816, 0.610 to 0.758, and 0.640 to 0.764 for Chinese, Malay, and Indian, respectively. D4S2364 is the least polymorphic markers; however, it still achieved a heterozygosity of greater than 0.6. The combined random match probability (RMP) of the six miniSTR were calculated to be 4.6 x 10 to the minus 6 power, 3.5 x 10 to the minus six power, and 4.2 x 10 to the minus six power, and the combined power of exclusion was 97.77 percent, 96.68 percent, and 97.55 percent for Chinese, Malay, and Indian, respectively. The locus D2S441 showed the most significant differentiation for all three population pairs, and D1S1677 is not significant for all. The Chinese-Malay pair has no significant differentiation for all markers except D2S441. Venous blood was obtained from randomly selected Singapore Armed Forces personnel composed of 185 Chinese, 182 Malay, and 178 Indian individuals. 4 tables and 7 references
Main Term(s): Forensics/Forensic Sciences
Index Term(s): Victim identification ; Suspect identification ; Investigative techniques ; DNA fingerprinting ; Foreign criminal justice research ; Parentage determination ; NIJ grant-related documents ; Singapore
   
  To cite this abstract, use the following link:
https://www.ncjrs.gov/App/Publications/abstract.aspx?ID=263230

* A link to the full-text document is provided whenever possible. For documents not available online, a link to the publisher's web site is provided.