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  NCJ Number: NCJ 241212     Find in a Library
  Title: Prediction of Eye Color from Genetic Data Using Bayesian Approach
  Document URL: HTML 
  Author(s): Ewelina Pospiech, M.S. ; Jolanta Draus-Barini, M.S. ; Tomasz Kupiec, Ph.D. ; Anna Wojas-Pelc, Ph.D., M.D. ; Wojciech Branicki, Ph.D.
  Journal: Journal of Forensic Sciences  Volume:57  Issue:4  Dated:July 2012  Pages:880 to 886
  Date Published: 07/2012
  Page Count: 7
  Annotation: This article examined two alternative Bayesian network model variants developed and evaluated for their accuracy in prediction of eye color.
  Abstract: Prediction of visible traits from genetic data in certain forensic cases may provide important information that can speed up the process of investigation. Research that has been conducted on the genetics of pigmentation has revealed polymorphisms that explain a significant proportion of the variation observed in human iris color. Here, on the basis of genetic data for the six most relevant eye color predictors, two alternative Bayesian network model variants were developed and evaluated for their accuracy in prediction of eye color. The first model assumed eye color to be categorized into blue, brown, green, and hazel, while the second variant assumed a simplified classification with two states: light and dark. It was found that particularly high accuracy was obtained for the second model, and this proved that reliable differentiation between light and dark irises is possible based on analysis of six single nucleotide polymorphisms and a Bayesian procedure of evidence interpretation. Abstract published by arrangement with John Wiley & Sons.
  Main Term(s): Forensics/Forensic Sciences
  Index Term(s): Prediction ; Medical research ; Scientific techniques ; DNA fingerprinting
  Type: Report (Technical Assistance)
  Country: United States of America
  Language: English
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