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NCJ Number: NCJ 242046     Find in a Library
Title: Postmortem Vitreous Beta-Hydroxybutyrate: Interpretation in a Forensic Setting
Journal: Journal of Forensic Sciences  Volume:57  Issue:5  Dated:September 2012  Pages:1234 to 1240
Author(s): Michael Heninger, M.D.
Date Published: 09/2012
Page Count: 7
Document: HTML 
Type: Report (Technical)
Language: English
Country: United States of America
Annotation: Vitreous beta-hydroxybutyrate (BHB) was retrospectively analyzed in 1,795 forensic cases using the Pointe Scientific method.
Abstract: Vitreous beta-hydroxybutyrate (BHB) was retrospectively analyzed in 1,795 forensic cases using the Pointe Scientific method. Comparison of vitreous BHB with vitreous glucose in 1,781 of the cases showed moderately good correlation r = 0.731. Comparison with blood alcohol levels in 1,561 of the cases showed no correlation r = -0.053. Vitreous BHB was a marker of diabetic ketoacidosis when above 6.0 mM with a vitreous glucose over 200 mg/dL. It was an indicator (greater than 50 percent) for alcoholic ketoacidosis when above 6.0 mM with a vitreous glucose below 200 mg/dL. Recommendations for interpretation of vitreous BHB: less than 0.4 mM normal; 0.41–1.2 mM slightly elevated, rarely (less than 1 percent) of concern; 1.21–2.0 mM moderately elevated, less rarely (2.5 percent) of concern; 2.01–6.0 mM significantly elevated, frequently of concern (12–48 percent); greater than 6.0 mM usually (100 percent in this study) indicated life-threatening conditions. Vitreous BHB was helpful evaluating cases with ketogenic conditions, especially diabetes and alcoholism. Abstract published by arrangement with John Wiley & Sons.
Main Term(s): Forensics/Forensic Sciences
Index Term(s): Blood/body fluid analysis ; Alcoholism ; Diseases ; Scientific techniques ; Death investigations
   
  To cite this abstract, use the following link:
https://www.ncjrs.gov/App/Publications/abstract.aspx?ID=264208

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