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NCJ Number: NCJ 242050     Find in a Library
Title: Toxicology and Characteristics of Deaths Involving Zolpidem in New South Wales, Australia 2001–2010
  Document URL: HTML 
Author(s): Shane Darke, Ph.D. ; Mark Deady, B.Psych. ; Johan Duflou, M.Med.Path.
  Journal: Journal of Forensic Sciences  Volume:57  Issue:5  Dated:September 2012  Pages:1259 to 1262
Date Published: 09/2012
Page Count: 4
  Annotation: This study examined cases presented to the New South Wales Department of Forensic Medicine between January 1, 2001 and September 31, 2010 in which zolpidem was detected.
Abstract: All cases presenting to the New South Wales Department of Forensic Medicine between January 1, 2001 and September 31, 2010 in which zolpidem was detected, were retrieved. A total of 91 cases were identified. The mean age was 49.4 years, 65.9 percent were male, and 61.5 percent were suicides. Zolpidem was a factor contributing to death in 35 (37.3 percent) cases, of which 31 (34.1 percent) involved zolpidem toxicity. The median blood zolpidem concentration was 0.20 mg/L (range 0.05–3.50 mg/L), with no significant gender difference. Drug toxicity cases involving zolpidem had significantly higher median blood zolpidem concentrations than other cases (0.50 vs. 0.10 mg/L). In 83.5 percent of cases, psychoactive substances other than zolpidem were detected, most commonly antidepressants (46.2 percent), benzodiazepines (35.2 percent), opioids (26.4 percent), and alcohol (39.6 percent). In summary, zolpidem was a factor contributing to death in a large proportion of cases, predominately involving drug toxicity and suicide. Abstract published by arrangement with John Wiley & Sons.
Main Term(s): Forensics/Forensic Sciences
Index Term(s): Suicide ; Drug effects ; Toxic reactions ; Drug analysis ; Prescription drugs ; New South Wales
Type: Report (Study/Research)
Country: United States of America
Language: English
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