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NCJ Number: NCJ 242072     Find in a Library
Title: Death Following Injection Sclerotherapy Due to Phenol Toxicity
  Document URL: HTML 
Author(s): Abraham T. Philip, M.D. ; Jeanna M. Marraffa, Pharm.D.
  Journal: Journal of Forensic Sciences  Volume:57  Issue:5  Dated:September 2012  Pages:1372 to 1375
Date Published: 09/2012
Page Count: 4
  Annotation: Prolapse rectum (PR) or protrusion of the rectum beyond the anus occurs frequently in populations at both extremes of age.
Abstract: Prolapse rectum (PR) or protrusion of the rectum beyond the anus occurs frequently in populations at both extremes of age. In the pediatric population, in developed countries, the commonest cause for PR is thought to be cystic fibrosis (CF). Treatment options for CF include conservative management, surgical resection and fixation, suturing, and injection sclerotherapy (IS). The last is considered an attractive treatment option because it is minimally invasive. In this case report, the authors present the details about a 2-year-old female child, with PR and CF, who died after IS, using phenol as the sclerotherapeutic agent. Autopsy findings and toxicology tests performed to establish phenol toxicity are documented. The available literature is reviewed. This case report underscores the risks of using phenol for IS and emphasizes the point that the procedure is not innocuous and an adverse outcome including fatality is a possibility. Abstract published by arrangement with John Wiley & Sons.
Main Term(s): Forensics/Forensic Sciences
Index Term(s): Drug effects ; Autopsy ; Treatment ; Sudden infant death syndrome ; Forensic pathology
Type: Case Study
Country: United States of America
Language: English
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