Between 1982 and 1985, marijuana consumption declined an estimated 4 percent, due in large part to eradication and interdiction efforts. The overall supply also declined. Mexico and Columbia were leading producers of available marijuana. In 1985 and 1986, cocaine was readily available. There were significant increases in hospital emergencies, which also indicated increases in the smoking of cocaine base. Worldwide cocaine production was estimated at 251-273 metric tons, with Columbia remaining the principal producer and distributor. Illicit manufacture and distribution of methamphetamine continued to increase, while depressant use declined. Heroin-related hospital emergencies increased, and the use of heroin in combination with other drugs remained a serious problem. Southwest Asia, Mexico, and the Golden Triangle (Burma, Laos, and Thailand) were the principal producers of opium. Trends for 1985-1986 are expected to continue in 1987. 27 figures.