Following a discussion of the credibility and management problems involved in the use of such witnesses, guidelines are provided for the initial contact between accomplice or informant and the prosecutor, negotiating a deal, documentation of the agreement, extracting information from the witness, testing and corroborating the witness' story, and managing the witness' environment. Trial tactics then are discussed, including motions in limine, voir dire, opening statements, jury instructions, direct examination, corroboration, witness preparation for cross-examination, and final and rebuttal arguments. Emphasis is placed on the importance of corroborating evidence and the informant's motives in cooperating as a means for enhancing witness credibility and successful prosecution.