The substantive due process issues in Roe v. Wade include the constitutional right, if any, to abortion and the State's role in protecting a woman's right to terminate a pregnancy. The legal implications of these issues are discussed as well as collateral medical concerns such as the timing of abortions, abortion methods, and the duties owed to fetuses that are alive after the abortion is completed. The rights and personhood status of fetuses are also discussed, along with such issues as in vitro fertilization and the disposition of extracorporeal embryos. The debate over Roe v. Wade has failed to focus on the procreative interests at issue and the varying status of human embryonic existence. These issues require reasoned analysis. 82 footnotes.