In addition, social marketing principles should be used to tailor messages to specific audiences, and these messages should be integrated with programs if they are to achieve the greatest possible effects. Although few cases of AIDS exist in adolescents, the long incubation period between HIV infection and an AIDS diagnosis means that many young adults with AIDS were probably infected while teenagers. In addition, research on sexual activity and drug use among adolescents shows the importance of efforts directed at this population. Runaway youth, black and Hispanic adolescents, and disadvantaged youth are at particular risk of HIV infection. Evaluations of existing programs to prevent teenage pregnancy, smoking, and cardiovascular disease have shown the importance of targeting audience subgroups, using many avenues for intervention and integrating messages and programs so that they support each other. These findings should be incorporated into a comprehensive strategy for AIDS prevention as well. 61 references.