NCJ Number
128097
Journal
Journal of Forensic Sciences Volume: 36 Issue: 1 Dated: (January 1991) Pages: 153-165
Date Published
1991
Length
9 pages
Annotation
Two artificial intelligence programs are compared with a discriminant analysis program for accuracy in predicting dose from blood or plasma amitriptyline and nortriptyline concentrations. The programs used the same data from dogs given therapeutic, toxic, and fatal doses of amitriptyline.
Abstract
While all programs achieved a high success rate, ranging between 77 and 93 percent correct assignments, in recording data in the high, low, or middle dose groups, two programs also gave a probability associated with the outcome. The results indicate that blood amitriptyline and nortriptyline concentrations are most effective in estimating the dosage in acute amitriptyline overdoses. 6 tables, 6 figures, and 5 references (Author abstract modified)