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Longitudinal Studies of HIV Infection in Intravenous Drug Users: Methodological Issues in Natural History Research

NCJ Number
136001
Editor(s)
P Hartsock, S G Genser
Date Published
1991
Length
157 pages
Annotation
These nine papers examine the methodological problems involved in conducting natural history studies of HIV infection in intravenous drug abusers.
Abstract
Individual papers present a history of natural history studies dealing with AIDS and drug abuse with emphasis on the unprecedented interdisciplinary nature of these studies and describe the main types, strengths, and limitations of longitudinal and case-control studies. Further papers examine similarities and differences in intravenous drug users and homosexuals and bisexuals and the implications for conducting research, other infections and HIV-related complications that do not meet the definition of the Centers for Disease Control, and sampling issues involved in studying drug users and corroboration of drug use. Other papers consider the issue of corroboration, the degree of "socially desirable" responding, potential cofactors in the outcomes of HIV infection in intravenous drug users, mathematical models, and data gaps. Tables, chapter reference lists, and list of other NIDA publications