The United States' experience with alcohol is the strongest argument against the legalization of currently illicit drugs. During alcohol prohibition in the 1920's, alcohol-related mental and physical illness declined dramatically. The incidence of these illnesses soared, however, after the repeal of Prohibition in 1933. This historical case study indicates that greater availability results in greater use and abuse. Another case study of what happens under government regulated and controlled systems for drug distribution is the prescription drug system. Prescription drugs have been identified in more drug-related deaths and emergency medical situations than all illegal drugs combined. Over 20 million Americans use prescription drugs for nonmedical reasons. This problem stems from the misuse of prescription drugs and the diversion of controlled substances to the illicit market. The legalization of drugs would not only increase their availability and thus their debilitating effects, it would also increase the level of violent crimes and property crimes. Drug use itself rather than the need to obtain money for drugs is the greater cause of drug-related crime. Expanded drug use under legalization would also increase on-the-job accidents and contribute to other accidents caused by diminished physical and mental faculties under the influence of drugs. 76 footnotes