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DINUCLEOTIDE REPEAT POLYMORPHISM AT THE APOLIPOPROTEIN A II LOCUS -- PHENOTYPING FROM PERIPHERAL BLOOD AND HAIR

NCJ Number
142431
Journal
Japanese Journal of Legal Medicine Volume: 46 Issue: 1 Dated: (February 1992) Pages: 1-6
Author(s)
K Kurosaki; K Washio; S Misawa; S Ueda
Date Published
1992
Length
6 pages
Annotation
The genomes of human eukaryotes contain very short simple sequence repeats including (dA-dC) and (dG-dT)n. Recent research has found that these repeats exhibit marked length polymorphism due to wide variation in their reiteration numbers.
Abstract
Peripheral blood samples were collected from 60 Japanese individuals to examine dinucleotide repeat polymorphism at the apolipoprotein AII locus. The informativeness in Japanese was as high as in Caucasians (PIC value and heterozygosity of 0.67 and 0.72, respectively), but their allele frequencies were different, to a statistically significant degree. These findings demonstrate the advantages of using dinucleotide repeat polymorphisms in forensic science because a phenotype can be determined not only from a single hair root but from a short hair shaft. 2 tables, 2 figures, and 19 notes

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