The Clean Air Act imposes penalties on those who knowingly violate Federal or State regulations designed to achieve ambient air-quality standards established by the U.S. Environmental Protection Agency. The Federal Water Pollution Control Act, the Rivers and Harbors Act of 1899, and the Safe Drinking Water Act together protect the quality of the Nation's surface and groundwater. Under the Resource Conservation and Recovery Act, criminal penalties are imposed on persons who improperly transport, store, or treat hazardous wastes. The Comprehensive Environmental Response, Compensation and Liability Act mandates the cleanup of hazardous substances at contaminated sites. The Toxic Substances Control Act addresses the manufacture, processing, and distribution or disposal of chemicals that pose an unreasonable risk of injury to the public or environment. The manufacture, registration, transportation, sale, and use of toxic pesticides is regulated by the Federal Insecticide, Fungicide and Rodenticide Act. 447 footnotes