The authors discuss ambiguities in regulatory theory and specifically apply this theory to cases involving deaths at multiple employer work sites in Australia. They consider economic rationalism in modern economies and note a fundamental tenet of economic rationalism is that market forces rather than governments should determine organizational structure at all levels of society. Having reviewed research on corporate or white-collar crime, the authors conclude strategies to reduce such crime should go beyond the enactment and enforcement of criminal law. Concepts of regulation, responsibility, and crime prevention should be reassessed because it is not realistic to expect a corporation to maintain a truly ethical stance if ethics undermine economic viability. Like regulation, white-collar crime prevention should not be limited to specific programs and strategies but should have broader political and structural dimensions. 78 references, 3 tables, and 1 figure