This guide first provides guidelines for writing effective requests for proposals (RFP's) for the sub-granting process. RFP's should request grant applicants to address the following information in their proposals: project objectives, the nature of the underage drinking problem in the community, causes of the identified alcohol-related problems, how the community is currently addressing the problem of underage drinking, strategies the community will implement as a result of grant funding, how proposed strategies relate to the perceived causes of existing underage drinking problems, and how media will be used to enhance proposed strategies. After presenting these guidelines for RFP's, this guide contrasts two project case studies, one designed to reduce binge drinking among high school and underage college students in a small college town and the other designed to reduce alcohol-related traffic crashes among youth. A lesson drawn from the case studies is that the lead agency in the State can help communities to develop cohesive, well-articulated, and effective plans to reduce underage alcohol use. State leadership and oversight can provide a clear and logical framework for funding applications.