"Oregon's Guidelines for Effective Gender-Specific Programming for Girls" (2000) and the accompanying manual on how to apply them are designed to assist organizations that work with girls 10- to 19-years-old in the construction of program design, practices, and evaluation. All the guidelines are interconnected and build on each other to create an environment that can enhance and maximize program effectiveness for girls. The guidelines apply to a wide range of services, from community-based prevention programs for at-risk girls to intensive residential programs, detention, and State institutions for girls and young women. The guidelines are divided into two sections: administration and management of gender-specific programs and program content. The guidelines take into account the distinctive and prevalent needs of female juvenile offenders, such as eating disorders; depression; the use and abuse of alcohol, drugs, and tobacco; victimization from violence and abuse; and the experiences of homelessness, running away from home, and prostitution. This article presents and explains the guidelines under the following topics: program structure, staff qualifications regarding female issues, program content, strength-based programming, and health-based programming. 12 notes