Vast amounts of information are now transferred regularly through digital connections, especially e-mail. Such a practice, while advantageous in some respects, affects business practices because it has replaced direct personal communication. The article explores how to handle the stress of high-tech communications, with a special focus on managers and supervisors. It focuses on stress-mitigation practices, such as setting aside time to do e-mail based on your schedule. Other practices include unsubscribing from generic mailing lists and deleting messages that do not require a response. A textbox is included that offers 10 tips for successful e-mail business correspondence. A discussion of strategies an organization can employ to reduce computer stress follows the tips for managers. The e-mail practices of upper management should set the tone for the type and frequency of e-mail interaction that occurs on the job. Another textbox outlines the most important points about e-mail stress. With proper use, e-mail’s advantages can be realized without compromising business practices.