The textbook focuses on the science of forensic DNA typing methods, including the biology, technology, and genetic interpretation of short tandem repeat (STR) markers. These methods are the most widespread DNA analysis methods currently used. The textbook is intended for forensic scientists, law enforcement professionals, legal professionals, and college students who are eager to gain a better understanding of STRs. The materials contained in the book can also assist forensic DNA laboratories in meeting the training requirements stated in the DNA Advisory Board Quality Assurance Standards, which requires DNA examiners to have training in biochemistry, genetics, and molecular biology. There are three main sections covering the biology, technology, and genetics of STR markers. An overview of the science and history of DNA and how it is used in forensic identification is provided. The biology section includes chapters 2 through 11, which focus on basic DNA structure and function, as well as the processes involved in the preparation of samples for DNA amplification. The biology of STR markers is described, as are the main issues of the forensic DNA community, such as contamination and degraded samples. The section on technology, spanning chapters 12 through 18, focuses on various DNA analysis instruments. Fluorescent detection methods are described and alternative DNA analysis technologies are reviewed, including mass spectrometry and microchips. This section also touches on the use of computer DNA databases to investigate crimes. The genetics and statistical analysis section includes chapters 19 through 23 and reviews genetic principles and statistics before discussing calculations for DNA profile frequency estimates. All sections contain clear examples demonstrating how the techniques are applied. The seven appendixes contain important supplemental materials. References, figures, boxes, tables, appendixes, index