The largest component of admixture based on MtDNA analysis came from the four major haplogroups previously observed in Native American ancestry, including A (29.3 percent), B (15.7 percent), C (20.6 percent), and D (4.8 percent). European (17.8 percent) and African (11.8 percent) were also observed within this dataset. The descriptive analyses found that the SWGDAM Hispanic dataset is similar to published Native American and Hispanic datasets. Of the 686 individuals in the dataset, 245 came from Texas or New Mexico, with the remainder coming from Connecticut (n=148), Illinois (N=5), or from an unknown location (n=288). In comparing SWGDAM Hispanic samples from the Southwest with other SWGDAM Hispanic samples, a greater percentage of Native American haplogroups were present (79.9 percent); and there were fewer African-American haplogroups (4.5 percent). A total of 234 SNPs were found in the dataset, including 36 newly reported variable positions. The SNPs ranged from having 1 to 31 changes on the phylogenetic tree, with site 16519 having the most variation. There was an average of 3.9 character changes for each variable position on the tree. The most variable sites (13 or more changes each listed from fastest to slowest) by length (L) were 16519 (L=31), 16189 (L=23), 152 (L=23), 16311 (L=19), 146 (L=17), 195 (L=17), 16093 (L=15), 16362 (L=14), 16129 (L=13), 150 (L=13), and 153 (L=13). A total of 27 SNPs were selected to identify all clusters that contained 1 percent (N=7) or more individuals in the Hispanic data set. The report's description of research methodology addresses data availability, phylogenetic methods, sequence alignment, and the ranking of SNPs. 5 tables and 65 references