Findings indicate that FLX and COMB accelerated treatment response compared with PBO, and COMB accelerated response relative to CBT alone. Based on pharmacotherapist scores on the Clinical Global Impression-Improvement Scale (CGI-I), COMB and FLX showed faster onset of benefit than PBO on both the time to response and time to stable response, and COMB was faster than FLX in achieving stable response. The probability of sustained early response was approximately three times greater for COMB than PBO, two times greater for FLX than PBO, and 1.5 times greater for COMB than FLX. On the psychotherapist CGI-I scores, both first response and stable response occurred faster in COMB than CBT, with a probability of sustained early response approximately three times greater for COMB than CBT. Response was defined as "very much improved" or "much improved" on the CGI-I. Survival analyses, as determined by Cox proportional hazards models, and Kaplan-Meier curves were conducted to assess time to first response and time to stable response. Direct comparisons between pharmacotherapy and CBT were not made because of differences in visit schedules. 2 tables, 2 figures, and 16 references