Results indicated that the presence of co-occurring domestic violence significantly impacted workers’ assessments of the degree of responsibility for child maltreatment, particularly in terms of inadequate supervision, for exposing the child to domestic violence, and for males, for causing physical harm to the child. The findings also revealed that neither the severity of injury to the child nor the caregiver’s response to the injury had an influence on workers’ assessments of responsibility for maltreatment. This finding contradicts previous research that found severity of injury and caregiver’s attitude to be related to the substantiation of child maltreatment. On the other hand, parental substance abuse significantly influenced worker’s substantiation decisions and their concerns for recurrence of maltreatment. The findings suggest that greater emphasis should be placed on assessing the dynamics of domestic violence and substance abuse during child protective investigations. Future research should utilize field methods to explore the “how” and “why” of the effects of different factors on the decisionmaking process of child welfare workers. The research involved systematically sampling 87 public child welfare workers from a list of current front line child welfare employees in a Midwestern State. Participants were asked to rate vignettes/scenarios regarding male and female caregivers’ responsibility for three different types of child maltreatment. The vignettes were developed by randomly assigning characteristics believed to be related to evaluations about responsibility for child maltreatment. The three forms of child maltreatment included in the vignettes were: (1) inadequate child supervision; (2) causing physical harm to the child; and (3) exposing the child to domestic violence. The vignettes rather than the child welfare workers were used as the unit of analysis, which means the total sample size was 435 case vignettes. Ordinary least squares regression models were used to analyze the data. Tables, references