First, the article lists nine typical characteristics of a letter or package that ought to trigger suspicion. These include a powdery substance on the outside, excessive postage, a handwritten or poorly typed address, and strange odors or stains. Advice is offered on what to do if a letter or package is suspected of being a threat. These include not trying to open the mail piece, isolating it, evacuating the immediate area, and calling a postal inspector to report the suspicious mail. Specific information is provided on anthrax. The characteristics of anthrax and symptoms of exposure to it are described, along with the features of treatment. Suggestions are offered for limiting physical exposure of the mailroom to suspected anthrax mailings. One recommendation is to identify a single point of contact for opening mail. Also, if possible, do not open mail in an area where other personnel are present. Have appropriate gloves available for individual use, and screen all mail for suspicious packages. For organizations with a central mailroom for all incoming mail, vulnerability assessments should be regularly performed in order to determine whether the organization or a particular employee is a potential target. Develop mail-center handling techniques and procedures for items identified as suspicious based on screening criteria. In addition, conduct unannounced tests for mail-center personnel.