The findings indicated that antisocial behavior and depression had considerable continuity in middle adolescence. Concurrent comorbidity between depression and antisocial behavior was also remarkable. Among girls, depression predicted subsequent antisocial behavior in a 2-year span, but among boys depression seemed to protect them from subsequent antisocial behavior. A Finnish modification (RBDI of the 13-item Beck depression inventory (BDI) was used to assess depression. The research consisted of surveys at two waves (T1 and T2) during a 2-year period followup during the school year 2002-2003 (T1) and during the school year 2004-2005 (T2) of 2,070 adolescents. The results of this study offer implications for the prevention and treatment of adolescent depression and antisocial behavior. Previous studies have established that both depression and antisocial behavior in adolescence have considerable continuity. However, findings of previous studies on comorbidity and longitudinal associations between adolescent depression and antisocial behavior have been inconsistent, especially with regard to gender differences. The purpose of this study was to investigate continuity, comorbidity, and longitudinal associations between depression and antisocial behavior using data from a 2-year longitudinal study with adolescent boys and girls. Tables, references