Cocaine is a powerfully addictive stimulant drug. The powdered hydrochloride salt form of cocaine can be snorted or dissolved in water and injected. Crack is cocaine base that has not been neutralized by an acid and comes in the form of a rock crystal that is heated to produce vapors, which are smoked. According to the 2006 National Survey on Drug Use and Health, 35.3 million Americans aged 12 and older reported having used cocaine, and 8.5 million reported having used crack. This fact sheet provides an informational overview of the drug’s use, effects on the brain and on the general health of the body, treatment options, and national statistics on the widespread abuse of cocaine. Notes, and reference