Highlights of findings include: (1) intimate partner violence (IPV) serves as a risk factor for excessive drinking and a consequence from drug use for male and female college students; (2) alcohol and drug use was associated with risky sexual behaviors with students who drank and used drugs were likely to have sex with a stranger, a one-night stand, and difficulty recalling sexual encounters with both familiar and unfamiliar partners; (3) victimized male and female students were more likely to drink alcohol, use drugs, and engage in risk-taking behaviors compared to nonvictimized male and female students; and (4) survey data adds to previous research in this area by providing information about the direct and indirect relationships among IPV, alcohol and drug use, and other health-compromising behaviors for male and female students enrolled at a metropolitan teaching university. There has been a tremendous amount of prevention research on risk factors for excessive drinking among first-year students, however, there is little research on IPV, alcohol and other drug use, and health-compromising behaviors for male and female college students. This is one of the first studies to investigate the direct and indirect relationships among IPV, alcohol and drug use, and other health-compromising behaviors for male and female students. Tables and references