Today, the use of DNA technology is growing in every country around the world. The growth in the power of DNA testing is based not only upon technological improvements, but also in the understanding of how the results of DNA testing can be used in legal-judicial settings to address individual crimes, as well as helping to reveal patterns associated with genocide, systematic rapes, and other widespread acts of violence. As technological improvements continue, and as how to interpret patterns revealed by DNA testing become better understood and accepted, forensic DNA testing will have an ever increasing impact on nation and international legal development, justice, and accountability. This article examines the early use and acceptance of DNA technology as first applied to human sources, the evolution of DNA databases with improved technology, the use of DNA testing on mass crimes, and with the rapid improvement in DNA technology the expanded international database development.