The results of the study showed that early elementary factors across different theoretical domains were predictive of depression severity 7 years later. However, most of the significant predictors were from the individual characteristic group, with some of the factors affecting adolescent depression differently for males and females, especially antisocial behavior for females. The overall findings indicate that selected family environment, individual characteristics, and psychological functioning day-to-day predictors during the elementary school years are related to adolescent mental health, specifically depression. Focusing on the developmental factors that lead to or are related to emergence of depression over time for school-based children, this study examined the longitudinal relationship of early elementary predictors to adolescent depression 7 years later. The sample consisted of 938 students who have been part of a larger longitudinal study that started in 1993. Figures, tables, notes, and references