This report presents the Office of National Drug Control's (ONDCP) ADAM II program results and provides information to law enforcement agencies, treatment service providers, and policymakers making decisions about the problems their communities face. Findings reflect data on over 4,700 male arrestees 18 years and older at the point of their involvement in the criminal justice system who were interviewed between April 1 and September 30, 2010. Collecting data at the point of arrest rather than during incarceration allows researchers to reliably detect drug use among the widest range of persons involved in criminal activity, many of whom will never move to incarceration, but rather will be released or move onto alternative or probationary status. ADAM II provides information that is specific to local and regional areas. ADAM II is the only Federal survey that offers a biological marker of recent use (urinalysis), which, when linked to interview data, validates information about recent drug use. In 2010, 88 percent of arrestees interviewed voluntarily provided a urine sample for testing. The ADAM II program collects data in 10 sites. All 10 sites were ADAM sites under the National Institute of Justice program from 2000 to 2003 and the data collection instruments, protocols, and sampling are those used since 2000. All interview data were collected by a professional interview staff in face-to face interviews conducted in the booking areas of large urban police stations and jails. Tables, figures, and appendix