Highlights from this report include: in 1992, 7,532 drug-abuse related deaths involving 17,995 drug mentions were reported to the Drug Abuse Warning Network (DAWN); of the 7,532 deaths, 74 percent were male, 56 percent were White, 29 percent were Black, and 13 percent were Hispanic; multiple drugs were reported in 75 percent of deaths, with cocaine reported in 46 percent of the drug-related deaths followed by alcohol-in-combination and heroin/morphine (39 percent of the deaths); overdoses accounted for 66 percent of the deaths with 56 percent of the deaths being accidental or unexpected; and the metropolitan areas with the greatest number of drug-related medical examiner cases in 1992 were New York, Los Angeles, Philadelphia, San Francisco, and Chicago. This report presents annual data on drug-abuse related medical examiner cases collected through DAWN for the calendar year 1992. Data were obtained from 137 medical examiners in 38 metropolitan areas located throughout the coterminous United States. Tables and appendixes