The study found that of the domains and facets of the five-factor model (FFM) of personality, agreeableness, conscientiousness, and neuroticism exhibited the strongest relations across antisocial behavior (ASB) and aggression. Agreeableness exhibited a moderate negative effect while conscientiousness exhibited a smaller negative effect. Neuroticism showed a smaller positive effect with regards to antisocial behavior and aggression, while extraversion and openness showed small but significant negative effects for aggression but not for antisocial behavior. The primary objective of this study was to determine whether any of the domains of the FFM of personality had any relation to antisocial behavior and aggression. Data were obtained from a meta-analysis of 53 studies that explored the relationship between the domains of FFM and ASB and aggression. The findings from this review are consistent with those of previous studies, providing strong support for using the FFM to understand ASB and aggression. Tables, figure, notes, and references