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NCJRS Abstract

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NCJ Number: 250479 Find in a Library
Title: Adapting Newborn Blood Testing Procedures to Forensic Toxicology
Corporate Author: RTI International
United States of America
Date Published: January 2017
Page Count: 1
Sponsoring Agency: National Institute of Justice (NIJ)
Washington, DC 20531
RTI International
Research Triangle Park, NC 27709
Grant Number: 2013-DN-BX-K017
Sale Source: National Institute of Justice (NIJ)
US Department of Justice
Office of Justice Programs
810 Seventh Street NW
Washington, DC 20531
United States of America
Document: HTML
Type: Program/Project Description; Report (Grant Sponsored); Report (Study/Research); Research (Applied/Empirical)
Format: Article; Document (Online)
Language: English
Country: United States of America
Annotation: This article reports the assessment of a procedure (“dried blood spot testing”), which has long been used by hospitals to test new-born babies for a host of diseases and genetic issues, to determine whether it could be useful in forensic toxicology examinations.
Abstract: In dried blood spot (DBS) testing of new-borns, a few drops of blood are taken from the baby’s heel, dried on paper, and then tested for the presence of diseases and genetic issues. Research funded by the National Institute of Justice (NIJ) examined dried blood spots for evidence of 28 drugs and metabolites. The goal was to determine whether DBS analysis could produce results comparable to traditional drug analysis and, when combined with mass spectrometry, be sufficiently sensitive for quantification of “drugs of abuse” typically encountered in forensic labs. The research showed that when using a technique called quantitative liquid chromatography-tandem mass spectrometry, the results with DBS were comparable to standard drug tests on whole blood. Because such a small sample of blood is required for a successful test, the method is particularly useful when only limited samples are available. This impacts the judicial system by allowing for toxicological analysis from samples that might otherwise go untested. In addition, because the DBS samples are small, they are easy to store. This is particularly beneficial for labs that must test and maintain large numbers of samples.
Main Term(s): Drug analysis
Index Term(s): Blood/body fluid analysis; Drug detection; Drug testing; Evidence preservation; NIJ grant-related documents; NIJ Resources
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