NCJ Number
30571
Journal
Japanese Journal of Legal Medicine Volume: 28 Issue: 6 Dated: (NOVEMBER 1974) Pages: 447-451
Date Published
1974
Length
5 pages
Annotation
STUDY OF THE CHEMICAL MECHANISMS UNDERLYING THE ADVERSE EFFECTS OF ETHANOL-BARBITURATE INTERACTION.
Abstract
THE STUDY INDICATED THAT THE PERMEABILITY OF CELL MEMBRANE AGAINST ETHANOL IS ALTERED BY THE BARBITURATE FOLLOWED BY A HIGHER ETHANOL CONTENT IN THE CELLS AND THAT THIS CHANGE OF DISTRIBUTION MAY BE CONTRIBUTORY TO THE MECHANISMS OF TOXICOLOGICAL INTERACTION BETWEEN ETHANOL AND THE DRUG. (AUTHOR ABSTRACT MODIFIED)