A comparative study was conducted on amphetamines; methamphetamines; MDMA (3,4-methylenedioxymethamphetamine); MDA (3,4-methylenedioxyamphetamine; MDE (3,4-methylenedioxyethylamphetamine); MBDB (N-methyl-1-[3,4-methylenedioxyphenyl]-2-butanamine); BDB (3,4-[methylenedioxypheny]-2-butanamine); PMA (4-methoxyamphetamine); DOM (2,5-dimethyloxy-4-methylamphetamine); DOB (4-bromo-2,5-dimethyloxyamphetamine); amphetaminil; pholedrine; fenfluramine; and amfepramone. The substances were analyzed to determine their specific threshold concentration for a positive detection in the Triage test, and their limit of detection and positive threshold concentration for the FPIA test and the results were compared. Furthermore, the capabilities of a more detailed analysis with the REMEDi system were studied. This HPLC system was able to produce information on the single drugs and main metabolites found in the sample, with the danger of false-positive or false-negative screening results greatly minimized. 3 tables, 1 figure, and 15 references