First responders to troubles in methamphetamine (meth) labs face significant dangers, from inhalation and contact with hazardous chemicals and gases to fire and explosions. Chemicals used to make meth can damage the central nervous system, liver, and kidneys, and burn or irritate the skin. Long-term exposure can cause cancer, short-term and permanent brain damage, and immune and respiratory system problems. There are many ways to produce meth and each carries its own inherent dangers, but the primary dangers are fire, contamination, and explosion. Preparing for action against meth production sites requires officers to know what the drug is, what dangers meth labs present, what protective clothing to wear in meth labs, and how to properly dispose of the chemicals. The article describes the dangerous people who run meth labs, the signs of a meth lab, and what to do or not to do. Meth labs require law enforcement to partner with local fire departments and emergency medical services. The Law Enforcement Training Institute's 2-day seminar on "Tactical Response to Methamphetamine Labs" provides information on the right way to deal with a meth lab from entry to decontamination to disposal.