DNA evidence has changed the way law enforcement collects and analyzes evidence. In Ottawa, the National DNA Data Bank contains the DNA profiles of over 46,000 convicted offenders, providing a key resource to investigators. DNA evidence is routinely compared to the evidence in the data bank; more than 1,000 “cold hits” have been made since the data bank opened in June 2000. The history of forensic science in Canada is briefly sketched as the author illustrates how far the profession has come since the first forensic “lab” opened in 1937. The current focus of the Canadian forensics team is on counterterrorism activities, which means that accurate and fast forensic information is critical for the safety of Canadian and American citizens. The article describes a recent case in which trace amounts of explosive materials were detected on a suspected terrorists’ clothing, helping law enforcement agents prevent an impending terrorist attack. The FLS also provides support to police agencies investigating chemical, biological, radiological, or nuclear events. Relatively new technology is being utilized with firearms; the Integrated Ballistics Information System (IBIS) can help link a suspect to a crime, a location, or a person by using laser optics and photo imaging to read and store the unique markings left on a bullet or cartridge case. Toxicology services are also important forensically; forensic toxicologists in Canada have been instructing police officers on how to detect drug impairment in suspects when alcohol has been ruled out. Finally, the article reflects on the past, present, and future of forensic work in Canada. One forensic scientist posits that the next revolution in forensic science will be DNA automation, allowing many more DNA samples to be analyzed than ever before. A textbox embedded within the article offers a timeline of forensic science in Canada.