The Amachi programs consist of three key elements: (1) the support and involvement of faith-based congregations from the youngsters' own or nearby neighborhoods; (2) the promotion of strong personal relationships between youth and their mentors; and (3) professional case management and support of the mentoring matches to ensure that the child, his/her family, and the mentor can all work together. This guide was developed to offer pragmatic, concrete, clear, and usable advice about establishing mentoring children-of-prisoners programs in local communities. It provides descriptions of best practices, along with explanations and illustrations of why these have worked in creating successful Amachi programs in a wide spectrum of communities. Three critical phases are presented and discussed: planning, building, and managing, along with resources and information for local planners. With its roots in Philadelphia, the Amachi program is a national model for mentoring children that has been implemented in 101 cities in 38 States. It recently spread its initiative to include the mentoring of children of prisoners; a group with many needs long unrecognized.