skip navigation

LIBRARY

Abstract Database

Register for Latest Research

Stay Informed
Register with NCJRS to receive NCJRS's biweekly e-newsletter JUSTINFO and additional periodic emails from NCJRS and the NCJRS federal sponsors that highlight the latest research published or sponsored by the Office of Justice Programs.

NCJRS Abstract

To download this abstract, check the box next to the NCJ number then click the "Back To Search Results" link. Then, click the "Download" button on the Search Results page. Also see the Obtain Documents page for direction on how to access resources online, via mail, through interlibrary loans, or in a local library.

 

NCJ Number: 250767 Find in a Library
Title: Linkage Disequilibrium Matches Forensic Genetic Records to Disjoint Genomic Marker Sets
Journal: PNAS  Volume:114  Issue:22  Dated:May 2017  Pages:5671-5676
Author(s): Michael D. Edge; Bridget F.B. Algee-Hewitt; Trevor J. Pemberton; Jun Z. Li; Noah A. Rosenberg
Date Published: April 2017
Page Count: 6
Sponsoring Agency: National Institute of Justice (NIJ)
Washington, DC 20531
Grant Number: 2014-DN-BX-K015
Sale Source: National Institute of Justice (NIJ)
US Department of Justice
Office of Justice Programs
810 Seventh Street NW
Washington, DC 20531
United States of America
Document: PDF
Type: Program/Project Description; Report (Grant Sponsored); Report (Study/Research); Research (Applied/Empirical)
Format: Article; Document (Online)
Language: English
Country: United States of America
Annotation: This report describes a method for identifying in distinct genetic datasets observations that represent the same person.
Abstract: With the increasing abundance of genetic data, the usefulness of a genetic dataset now depends in part on the possibility of productively linking it with other datasets. One issue that arises in combining multiple datasets is the record-matching problem, i.e., the identification of dataset entries that, although labeled differently in separate datasets, represent the same underlying entity. In a genetic context, record-matching involves the identification of the same individual genome across multiple datasets when unique identifiers, such as participant names, are unavailable. By using correlations among genetic markers close to one another in the genome, the method proposed in this report can succeed even when the datasets contain no overlapping marker. The authors show that the method can link a dataset similar to those used in genomic studies with another dataset containing markers used for forensics. The proposed approach can assist in maintaining backward compatibility with databases of existing forensic genetic profiles as systems move to new marker types. This approach illustrates that the privacy risks that can arise from the cross-linking of databases are inherent even for a small number of markers. 4 figures, 1 tables, and 39 references
Main Term(s): Forensic sciences
Index Term(s): Comparative analysis; Databases; DNA (Deoxyribonucleic Acid); DNA authentication; Investigative techniques; NIJ grant-related documents; NIJ Resources; Suspect identification; Victim identification
To cite this abstract, use the following link:
http://www.ncjrs.gov/App/publications/abstract.aspx?ID=272942

*A link to the full-text document is provided whenever possible. For documents not available online, a link to the publisher's website is provided. Tell us how you use the NCJRS Library and Abstracts Database - send us your feedback.