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NCJRS Abstract

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NCJ Number: 134642 Find in a Library
Title: Drugs of Abuse in Saliva: A Review
Journal: Journal of Analytical Toxicology  Volume:16  Dated:(January/February 1992)  Pages:1-9
Author(s): W Schramm; R H Smith; P A Craig; D A Kidwell
Date Published: 1992
Page Count: 9
Type: Research (Applied/Empirical)
Format: Article
Language: English
Country: United States of America
Annotation: Many illegal, addictive drugs including marijuana, cocaine, phencyclidine, opiates, barbiturates, amphetamines, and diazepines have been detected in saliva via analytical means including immunossay, gas chromatography/mass spectrometry, and then layer chromotography.
Abstract: However, the role of saliva in detecting drugs of abuse remains unclear because of variations in analytical methodology, the dose regimen of subjects, and the elapsed time between drug intake and sample collection. Use of saliva eliminates the issue of protection of privacy and of adulteration during sample collection. In contrast to urine as a medium, saliva can provide an estimate of the current level of intoxication. However, most drugs are retained in saliva for a shorter time than in urine, and concentrations of drugs are lower in saliva. Much information needs to be accumulated before scientific and technical guidelines for saliva analysis can be recommended. 6 tables, 3 figures, and 101 references
Main Term(s): Drug analysis; Saliva sample analysis
Index Term(s): Chromatography; Urinalysis
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