skip navigation


Register for Latest Research

Stay Informed
Register with NCJRS to receive NCJRS's biweekly e-newsletter JUSTINFO and additional periodic emails from NCJRS and the NCJRS federal sponsors that highlight the latest research published or sponsored by the Office of Justice Programs.

NCJRS Abstract

The document referenced below is part of the NCJRS Virtual Library collection. To conduct further searches of the collection, visit the Virtual Library. See the Obtain Documents page for direction on how to access resources online, via mail, through interlibrary loans, or in a local library.


NCJ Number: 136033 Find in a Library
Title: Comparison of Abbott Fluorescence Polarization Immunoassay (FPIA) and Roche Radioimmunoassay for the Analyses of Cannabinoids in Urine Specimens
Journal: Journal of Forensic Sciences  Volume:37  Issue:2  Dated:(March 1992)  Pages:632-635
Author(s): W T Budgett; B Levine; A Xu; M L Smith
Date Published: 1992
Page Count: 4
Type: Test/Measurement
Format: Article
Language: English
Country: United States of America
Annotation: Abbott fluorescence polarization immunoassay (FPIA) and Roche Abuscreen radioimmunoassay (RIA) were compared qualitatively with 142 urine specimens that contained 11-nor-delta-9-tetrahydrocannabinol-9-carboxylic acid, the major urinary metabolite of marijuana.
Abstract: A total of 142 specimens were analyzed by FPIA and RIA using the 100-ng/ml cut-off. The samples represented a range of concentrations above and below this administrative screening cut-off. Of the 142 specimens tested, 132 generated the same qualitative results. All specimens negative by FPIA and positive by RIA were within 20 percent of the cut-off, and seven of the nine specimens were within 10 percent of the cut-off. Similarly, the RIA counts per minute of the specimens negative by RIA and positive by FPIA were within 10 percent of the counts per minute produced by the cut-off calibrator. These data suggest that the RIA antibody might have slightly broader specificity in screening for cannabinoids; however, this slight difference is not significant. The study concludes that either of these immunoassays could be used singularly in a mass drug-screening laboratory and generate comparable results. 1 table, 1 figure, and 3 references
Main Term(s): Urinalysis
Index Term(s): Comparative analysis; Drug testing; Marijuana
To cite this abstract, use the following link:

*A link to the full-text document is provided whenever possible. For documents not available online, a link to the publisher's website is provided. Tell us how you use the NCJRS Library and Abstracts Database - send us your feedback.