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NCJRS Abstract

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NCJ Number: 148768 Find in a Library
Title: Toxicological Analysis for Drugs and Poisons Using the Formalin-Fixed Organ Tissues: 1. Methamphetamine
Journal: Japanese Journal of Legal Medicine  Volume:48  Issue:1  Dated:(February 1994)  Pages:33-37
Author(s): T Takayasu; T Ohshima; J Nishigami; T Kondo; Z Lin; M Ohtsuji; T Nagano
Date Published: 1994
Page Count: 5
Type: Report (Technical Assistance)
Format: Article
Language: English
Country: Japan
Annotation: Methamphetamine (MA) was analyzed using formalin-fixed tissues from the brain, lung, liver, kidney, and skeletal muscles of rabbits and an autopsied cadaver.
Abstract: The analysis used five different fixation periods: 1, 3, 7, 14, and 28 days. Results revealed that even 1 day after the formalin-fixation, the concentrations of MA in the fixed organ tissues already significantly decreased to 1.3 to 3.1 percent when compared to concentrations of MA in the nonfixed tissues, and to 0.04 percent to 0.4 percent in all the fixed organ tissues at 28 days after the fixation. Moreover, MA in the organ eluates from the autopsied male cadaver after 1-month formalin fixation was qualitatively detected. Results reveal and usefulness of MA detection using formalin-fixed organs in the practice of forensic medicine and police science. Figures, table, and 11 references (Author abstract modified)
Main Term(s): Science and Technology
Index Term(s): Amphetamines; Drug testing; Forensic medicine
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