skip navigation


Register for Latest Research

Stay Informed
Register with NCJRS to receive NCJRS's biweekly e-newsletter JUSTINFO and additional periodic emails from NCJRS and the NCJRS federal sponsors that highlight the latest research published or sponsored by the Office of Justice Programs.

NCJRS Abstract

The document referenced below is part of the NCJRS Virtual Library collection. To conduct further searches of the collection, visit the Virtual Library. See the Obtain Documents page for direction on how to access resources online, via mail, through interlibrary loans, or in a local library.


NCJ Number: 158001 Find in a Library
Title: Fifty Years of Development of Opium Characterization Methods
Journal: Bulletin on Narcotics  Volume:46  Issue:2  Dated:(1994)  Pages:79-108
Author(s): B Remberg; A Nikiforov; G Buchbauer
Date Published: 1994
Page Count: 30
Type: Historical Overview
Format: Article
Language: English
Country: United States of America
Annotation: This article reviews the rationale and preconditions for any practical and reliable characterization and origin-correlated classification of opium.
Abstract: The authors describe the results of the early international efforts under the aegis of the United Nations from 1951 to 1967, as well as the sporadic investigations in this direction since 1968. The authors show that in spite of the application of modern computer-based technology, the primary obstacle to comprehensive opium characterization and typology is still the lack of an extensive reference collection of opium samples of known origin. A comprehensive literature search by the authors in 1993 revealed that there is no reliable, rapid method for opium origin determination. They began experimental work on the topic in 1993, making use of a computer technique that has already proved its usefulness in many other kinds of multifactorial correlations. Two analytical approaches that apply this computer-aided evaluation method were adopted, one that used HPLC quantitation of the five major opium alkaloids and another that is based on quantitation of nitrogen-containing volatiles by gas chromatography with a nitrogen phosphorous detector. Subsequently, principal component analysis (PCA) was applied to evaluate the data and to correlate alkaloid concentrations to the origins of the samples. PCA is a multivariate evaluation method that allows the optimal presentation of numerous features of a sample in a two-dimensional graph after computer-aided data reduction; it is thus superior to the discriminatory functions of the United Nations research program. PCA can be valuable for future origin determinations provided that the appropriate computer technique and the corresponding data from a sufficient number of authentic opium samples are available. 1 table, 4 figures, and 79 references
Main Term(s): Drug analysis
Index Term(s): Drug law enforcement; Opioids
To cite this abstract, use the following link:

*A link to the full-text document is provided whenever possible. For documents not available online, a link to the publisher's website is provided. Tell us how you use the NCJRS Library and Abstracts Database - send us your feedback.