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NCJ Number: 165654 Add to Shopping cart Find in a Library
Title: Neurometric QEEG Studies of Crack Cocaine Dependence and Treatment Outcome (From Neurobiology of Cocaine Addiction: From Bench to Bedside, P 39-53, 1996, Herman Joseph and Barry Stimmel, eds. -- See NCJ-165651)
Author(s): L S Prichep; K Alper; S C Kowalik; M Rosenthal
Date Published: 1996
Page Count: 15
Sponsoring Agency: Haworth Press, Inc
Binghamton, NY 13904
National Institute on Drug Abuse
Bethesda, MD 20892-9561
Grant Number: RO1DA07707
Sale Source: Haworth Press, Inc
10 Alice Street
Binghamton, NY 13904
United States of America
Type: Research (Applied/Empirical)
Language: English
Country: United States of America
Annotation: This paper summarizes quantitative electrophysiological (QEEG) research on cocaine dependence conducted at Brain Research Laboratories of New York University Medical Center.
Abstract: The studies demonstrated cocaine-dependent subjects in the withdrawal state (without dependence on any other substance) had replicable abnormalities in brain function when evaluated at baseline approximately 5 to 10 days after last crack cocaine use. These abnormalities were characterized by significant excess of relative alpha power and deficit of absolute and relative delta and theta power. Abnormalities were greater in anterior than in posterior regions, and disturbances in interhemispheric relationships were also observed. In addition, QEEG subtypes were identified within the population of cocaine-dependent subjects at baseline, and these subtypes were significantly related to subsequent length of stay in treatment. The relationship between QEEG findings and the neuropharmacology of cocaine dependence is discussed. 57 references, 1 table, and 1 figure
Main Term(s): Drug effects
Index Term(s): Biological influences; Cocaine; Crack; Drug dependence; Drug treatment
Note: DCC
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