skip navigation


Register for Latest Research

Stay Informed
Register with NCJRS to receive NCJRS's biweekly e-newsletter JUSTINFO and additional periodic emails from NCJRS and the NCJRS federal sponsors that highlight the latest research published or sponsored by the Office of Justice Programs.

NCJRS Abstract

The document referenced below is part of the NCJRS Virtual Library collection. To conduct further searches of the collection, visit the Virtual Library. See the Obtain Documents page for direction on how to access resources online, via mail, through interlibrary loans, or in a local library.


NCJ Number: 182838 Find in a Library
Title: Pharmacology: Forensic Aspects of Drug Interactions, Part II
Journal: Forensic Examiner  Volume:8  Issue:11-12  Dated:November/December 1999  Pages:137-167
Author(s): Peter D. Anderson
Editor(s): Daphne Greenlee
Date Published: 1999
Page Count: 4
Type: Report (Technical)
Format: Article
Language: English
Country: United States of America
Annotation: This article discusses types of legal cases in which drug interactions are relevant, factors to consider when reviewing a case involving a drug interaction, examples of drug interactions, and clinical management of drug interactions.
Abstract: Drug interactions may be relevant in malpractice litigation, death or injury related to alleged intoxication, driving under the influence, homicides, suicides, and drug testing. Physicians, pharmacists, and nurses may be liable for failure to detect drug interactions. Further, drug interactions are relevant to substance abuse forensic work, and drug interactions need to be considered in death and suicide investigations. In analyzing drug interactions, forensic examiners should be careful when interpreting drug levels that are above or below the therapeutic range, especially since certain patients require higher or lower levels than the standard therapeutic range. Specific drug interactions are described for astemizole, monoamine oxidase inhibitors, serotonin, HIV protease inhibitors, theophylline, and ethanol. Four considerations in managing drug interactions are identified: (1) certain combinations of drugs are contraindicated and should never be given concurrently; (2) many drug interactions can easily be circumvented; (3) alternative drugs with less risk of interaction should be used; and (4) patient risk should be assessed and precautions should be taken to avoid adverse outcomes. 26 references
Main Term(s): Police
Index Term(s): Death investigations; Drug abuse; Drug effects; Drug related fatalities; Drug testing; Drug use; Forensic medicine; Forensic sciences; Malpractice litigation; Medical malpractice; Suicide; Toxic reactions
To cite this abstract, use the following link:

*A link to the full-text document is provided whenever possible. For documents not available online, a link to the publisher's website is provided. Tell us how you use the NCJRS Library and Abstracts Database - send us your feedback.